Transcription of human herpesvirus-like agent (HHV-8) in Kaposi's sarcoma.
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منابع مشابه
Transcription of human herpesvirus-like agent (HHV-8) in Kaposi's sarcoma.
Recently, DNA sequences of what appear to be a unique human herpesvirus-like agent (HHV-8) have been detected in different types of Kaposi's sarcoma (KS) tumors (Chang, Y., E.C. Cesarman, M.S. Pessin, F. Lee, J.C. Culpepper, D.M. Knowles, and P.S. Moore. 1994. Science (Wash. DC). 266:1865-1869). To further elucidate the possibility that HHV-8 plays a role in the pathogenesis of KS, the expressi...
متن کاملHuman herpesvirus 8 (HHV-8) detected in two patients with Kaposi's sarcoma-like pyogenic granuloma.
AIMS To report the finding of human herpesvirus 8 (HHV-8) in two patients with Kaposi's sarcoma (KS)-like pyogenic granuloma. This form of pyogenic granuloma closely resembles KS histologically and it has been reported that immunohistochemistry in such lesions may be positive for smooth muscle actin and factor VIII related antigen, which are typically negative in KS. In both patients the lesion...
متن کاملHuman herpesvirus 8 (HHV-8) and the etiopathogenesis of Kaposi's sarcoma.
OBJECTIVE To review the current literature on human herpesvirus 8 with particular attention to the aspects related to the etiopathogenesis of Kaposi's sarcoma. MATERIALS AND METHODS The authors searched original research and review articles on specific aspects of human herpesvirus 8 infection, including virology, epidemiology, transmission, diagnosis, natural history, therapy, and Kaposi's sa...
متن کامل[Human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus].
Human herpesvirus 8 (HHV-8), a gammaherpesvirus implicated in Kaposi's sarcoma, primary effusion lymphoma, and Castleman's disease, encodes several pathogenically important cellular homologs. To define the HHV-8 transcription program, RNA obtained from latently infected body cavity-based lymphoma 1 cells induced to undergo lytic replication was used to query a custom HHV-8 DNA microarray contai...
متن کاملHuman herpesvirus-8 (HHV-8) antibodies in women from São Paulo, Brazil. Association with behavioral factors and Kaposi's sarcoma.
BACKGROUND With the spread of AIDS, many HIV-infected women have been diagnosed with Kaposi's sarcoma (KS), especially in Africa. Since the discovery of a novel herpesvirus as the causative agent of KS (human herpesvirus 8 - HHV-8) several seroepidemiological studies have been conducted to identify groups at risk for KS. The risk for women in Brazil has not been studied. MATERIALS AND METHODS...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1996
ISSN: 0021-9738
DOI: 10.1172/jci118735